Arthrogryposis Multiplex Congenita – NORD (National Organization for Rare Disorders). #AMC

Originally posted 2016-06-04 11:29:17.

Arthrogryposis is a general or descriptive term for the development of nonprogressive contractures affecting one or more areas of the body prior to birth (congenitally). A contracture is a condition in which a joint becomes permanently fixed in a bent (flexed) or straightened (extended) position, completely or partially restricting the movement of the affected joint. When congenital contractures occur only in one body area, it is not referred to as arthrogryposis but rather an isolated congenital contracture. The most common form of an isolated congenital contracture is clubfoot. When arthrogryposis affects two or more different areas of the body, it may be referred to as arthrogryposis multiplex congenita (AMC). The most common form of AMC is Amyoplasia. Arthrogryposis and arthrogryposis multiplex congenita are sometimes used interchangeably.

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